The word “Amicogen” consists of the meaning of friend, “AMICO”
in Latin and of gene, “GENE”. We developed innovative biocatalysts
and proteins by applying our proprietary i DNA Evolution™ Technology.
We are a “Bioengineering company just like a Sincere Friend”
who contributes to the human health and the preservation of environment.
Amicogen Biotech R&D Center is expanding its R&D field based on
bio-platform technology, and researchers account for 30% of all employees.
We will lead the Industrial Biotechnology to develop new technologies
that can drive the development of humanity and society,
one step further than others.
Amicogen has developed Special Enzymes for industrial and pharmaceutical products based on the i DNA evolution™.
We want to contribute to the sustainable growth and lifelong health
of humanity by developing New Bio-Ingredientfor Health functional foods
with Special Enzymes and Protein Purification Resin.
As Amicogen started as a bio-venture company, we have focused on
the core competence of R&D and are pursuing sustainable growth
in innovative technologies and products. To increase the value
of enterprise and shareholder, we are continually strengthening our core competencies such as specialty enzyme business, healthcare, protein
purification resin business and others.
Amicogen promotes various activities to realize the value of contributing
to the protection of human health and the environment.
Amicogen is positioning itself as a global biotechnology company
through growth and leaps to create new values.
Amicogen has developed bio innovative technologies and operated the businesses that consider humankind and environment from the perspective of sustainability for the past 20 years. We will continue sustainable development based on Amicogen's environmental soundness, social responsibility and sustainable innovative technology.
Amicogen produces new technologies and values based on
creative thinking and constant technological innovation through human
oriented management. We do our best to ensure that talented individuals
with unique skills and abilities can demonstrate their abilities
according to the nature of their duties.
Amicogen produces new technologies and values based on
creative thinking and constant technological innovation through human
oriented management. We do our best to ensure that talented individuals
with unique skills and abilities can demonstrate their abilities
according to the nature of their duties.
We are developing Bio products and New Bio-Ingredients
using i DNA Evolution™ Technology.
OptioBio™ 40S 10x100
Prepacked OptioBio™ 40S 10x100 glass columns are designed for small-scale purification
as well as screening and optimization in bioprocess development and scale-up.
• Prepacked for reliable and reproducible results
• Optimal for high-performance small-scale purification and method optimization in bioprocess development
• High throughput and purity
Product
OptioBio 40S 10x100 column is prepacked with WorkBeads™ 40S resin for ion exchange chromatography (IEX).
The resin is designed for research and industrial scale purification of proteins,
peptides and nucleic acids and utilise the difference in their surface charge.
WorkBeads 40S is a strong cation exchange resin with sulfonate ligands.
WorkBeads are agarose based chromatographic resins manufactured using a proprietary method
that results in porous beads with a tight size distribution and high mechanical stability.
WorkBeads resins are designed for separations that require optimal capacity and purity.
Main characteristics of OptioBio 40S 10x100 and OptioBio 40Q 10x100 columns
| OptioBio 40S 10x100 | OptioBio 40Q 10x100 |
Target substance | Proteins and peptides | Protein, peptides and oligonucleotides |
Resin | WorkBeads 40S |
|
Matrix | Rigid, highly cross-linked agarose | Rigid, highly cross-linked agarose |
Average particle size (DV50)1 | 45 μm | 45 μm |
Ionic group (ligand) | Sulfonate (-SO3- ) | Quarternary amine (-N+(CH3)3) |
Ionic capacity | 0.18 - 0.25 mmol Na+/ml resin | 0.18 - 0.25 mmol Cl-/ml resin |
Dynamic binding capacity (DBC) | 150 mg BSA/ml resin2 | 47 mg BSA/ml resin3 |
Column volume (CV) | 7.9 ml | 7.9 ml |
Column dimension | 10 x 100 mm | 6 ml/min (450 cm/h) |
Recommended flow rate | 2 - 4 ml/min (150 - 300 cm/h) | 2 - 4 ml/min (150 - 300 cm/h) |
Maximum flow rate4 | 6 ml/min (450 cm/h) | 6 ml/min (450 cm/h) |
Column hardware pressure limit | 2.1 MPa, 21 bar, 305 psi | 2.1 MPa, 21 bar, 305 psi |
Chemical stability | Compatible with all standard buffers used for protein purification, 1 M NaOH, 30 % isopropanol or 70 % ethanol. Should not be stored at < pH 3 for prolonged time. | |
pH stability | 3 - 12 (working range) | 3 - 12 (working range) |
Storage | 2 to 25 °C in 20% ethanol | 2 to 25 °C in 20% ethanol |
1. The median particle size of the cumulative volume distribution.
2. Dynamic binding capacity determined in 20 mM Na-citrate, pH 4.0, at a flow of 2 ml/min (150 cm/h; 4 minutes residence time).
3. Dynamic binding capacity determined in 50 mM Tris-HCl, 50 mM NaCl, pH 8.0, at a flow of 2 ml/min (150 cm/h; 4 minutes residence time).
4. Maximum flow rate for aqueous buffers at 20 °C. Decrease the maximum flow rate if the liquid has a higher viscosity. Higher viscosities can be caused by low temperature. Use half of the maximum flow rate for 20% ethanol.
Product List
Product name | Size/Volume | Article Number |
OptioBio 40Q 10x100 | 7.9ml, Single | 55 410 011 |
OptioBio 40S 10x100 | 7.9ml, Single | 55 420 011 |