The word “Amicogen” consists of the meaning of friend, “AMICO”
in Latin and of gene, “GENE”. We developed innovative biocatalysts
and proteins by applying our proprietary i DNA Evolution™ Technology.
We are a “Bioengineering company just like a Sincere Friend”
who contributes to the human health and the preservation of environment.
Amicogen Biotech R&D Center is expanding its R&D field based on
bio-platform technology, and researchers account for 30% of all employees.
We will lead the Industrial Biotechnology to develop new technologies
that can drive the development of humanity and society,
one step further than others.
Amicogen has developed Special Enzymes for industrial and pharmaceutical products based on the i DNA evolution™.
We want to contribute to the sustainable growth and lifelong health
of humanity by developing New Bio-Ingredientfor Health functional foods
with Special Enzymes and Protein Purification Resin.
As Amicogen started as a bio-venture company, we have focused on
the core competence of R&D and are pursuing sustainable growth
in innovative technologies and products. To increase the value
of enterprise and shareholder, we are continually strengthening our core competencies such as specialty enzyme business, healthcare, protein
purification resin business and others.
Amicogen promotes various activities to realize the value of contributing
to the protection of human health and the environment.
Amicogen is positioning itself as a global biotechnology company
through growth and leaps to create new values.
Amicogen has developed bio innovative technologies and operated the businesses that consider humankind and environment from the perspective of sustainability for the past 20 years. We will continue sustainable development based on Amicogen's environmental soundness, social responsibility and sustainable innovative technology.
Amicogen produces new technologies and values based on
creative thinking and constant technological innovation through human
oriented management. We do our best to ensure that talented individuals
with unique skills and abilities can demonstrate their abilities
according to the nature of their duties.
Amicogen produces new technologies and values based on
creative thinking and constant technological innovation through human
oriented management. We do our best to ensure that talented individuals
with unique skills and abilities can demonstrate their abilities
according to the nature of their duties.
We are developing Bio products and New Bio-Ingredients
using i DNA Evolution™ Technology.
WorkBeads™ Protein A
WorkBeads™ Protein A resin is designed for purification of monoclonal-
and polyclonal antibodies using affinity chromatography technique.
For small scale purification and initial screening in process development we recommend
BabyBio A 1 ml and 5 ml columns prepacked with WorkBeads Protein A resin.
WorkBeads Protein A resin can also be used for applications in other formats,
such as test tube batch adsorption, spin columns, gravity columns or multi-well filter plates.
The resin can be used for immunoprecipitation experiments.
• High dynamic binding capacity for monoclonal and polyclonal antibodies with excellent recovery and purity
• Stronger coupling chemistry; high pH stability and low leakage
• Reliable, reproducible and efficient
Product
WorkBeads are agarose based chromatographic resins manufactured by a proprietary method
that results in porous beads with a tight size distribution and very high mechanical stability.
Agarose based matrices have been successfully used for decades in biotechnology research from
laboratory to production scale, due to their exceptional compatibility with biomolecules including
proteins, peptides, nucleic acids and carbohydrates.
WorkBeads resins are designed for separations requiring optimal capacity and purity.
The recombinant protein A attached to the resin is developed by Medicago
and produced in E. coli under conditions free of components of animal origin
and purified to high purity before coupling.
The protein A is engineered to facilitate an oriented coupling to the matrix.
This allows high binding capacities for target proteins.
The specificity of the recombinant protein A for the Fc region of IgG provides excellent purification.
Each batch of protein A is tested according to stringent requirements.
Main characteristics of WorkBeads Protein A resin.
|
WorkBeads Protein A |
Target substance |
Antibodies (IgG), bound via the Fc-region |
Matrix |
Rigid, highly cross-linked agarose |
Average particle size1 (Dv50) |
45 μm |
Ligand |
Recombinant protein A expressed in E. coli using animal-free medium |
Dynamic Binding Capacity2 (DBC) |
> 40 mg human IgG/ml resin |
Recommended flow rate3 |
250 cm/h |
Max flow rate4 |
500 cm/h |
Chemical stability |
Compatible with all standard aqueous buffers used for protein purification, |
pH stability |
3 - 10 (short term) |
Storage |
2 to 8 °C in 20 % ethanol |