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About Us
About Us
The word “Amicogen” consists of the meaning of friend, “AMICO”
in Latin and of gene, “GENE”. We developed innovative biocatalysts
and proteins by applying our proprietary i DNA Evolution™ Technology.
We are a “Bioengineering company just like a Sincere Friend”
who contributes to the human health and the preservation of environment.
Amicogen is the representative Industrial Biotechnology Company in Korea
and wants to contribute to the protection of human health and the environment. -
R&D
R&D
Amicogen Biotech R&D Center is expanding its R&D field based on
bio-platform technology, and researchers account for 30% of all employees.
We will lead the Industrial Biotechnology to develop new technologies
that can drive the development of humanity and society,
one step further than others.
Amicogen continues innovative research
and development for its first and best products. -
Products
Products
Amicogen has developed Special Enzymes for industrial and pharmaceutical products based on the i DNA evolution™.
We want to contribute to the sustainable growth and lifelong health
of humanity by developing New Bio-Ingredientfor Health functional foods
with Special Enzymes and Protein Purification Resin.
Amicogen develops Bio Products and
New Bio-Ingredients for Health functional food. -
Investors
Investors
As Amicogen started as a bio-venture company, we have focused on
the core competence of R&D and are pursuing sustainable growth
in innovative technologies and products. To increase the value
of enterprise and shareholder, we are continually strengthening our core competencies such as specialty enzyme business, healthcare, protein
purification resin business and others.
Amicogen strengthens key capacities
to increase enterprise value and shareholder value. -
Media
Media
Amicogen promotes various activities to realize the value of contributing
to the protection of human health and the environment.
Amicogen is positioning itself as a global biotechnology company
through growth and leaps to create new values.
You can find various looks and news of Amicogen
taking the initiative in the global bio industry. -
ESG
Sustainable management
Amicogen has developed bio innovative technologies and operated the businesses that consider humankind and environment from the perspective of sustainability for the past 20 years. We will continue sustainable development based on Amicogen's environmental soundness, social responsibility and sustainable innovative technology.
Amicogen wants to contribute to the protection of human health and the environment. -
Careers
Careers
Amicogen produces new technologies and values based on
creative thinking and constant technological innovation through human
oriented management. We do our best to ensure that talented individuals
with unique skills and abilities can demonstrate their abilities
according to the nature of their duties.
We are waiting for Amicogen people,
who will open new values and a bright future. -
CONTACT
Careers
Amicogen produces new technologies and values based on
creative thinking and constant technological innovation through human
oriented management. We do our best to ensure that talented individuals
with unique skills and abilities can demonstrate their abilities
according to the nature of their duties.We are waiting for Amicogen people,
who will open new values and a bright future.
Protein Purification Resin
Specialty enzyme
We are developing Bio products and New Bio-Ingredients
using i DNA Evolution™ Technology.
WorkBeads™ 40 IDA
CONTACT USWorkBeads™ 40 IDA resins are based on the iminodiacetic acid (IDA) chelating groups.
The resins can easily be charged, before use, with a broad spectrum of divalent or
trivalent transition metal ions, including Ni2+, Co2+, Cu2+ and Zn2+, Ga3+ or Fe3+.
They can then be used for the Immobilized Metal Ion Affinity Chromatography (IMAC)
purification of His-tagged proteins or other proteins with an affinity for metal ions.
, which are immobilized via a metal chelating ligand on the chromatography resin.
• Resin charged (or pre-charged) with the metal ion of choice
• High binding capacity and purity. Outstanding flow properties.
• Reliable and reproducible results
• Prepacked ready-to-use columns for rapid and reliable results - see BabyBio IMAC page Product
Product
The WorkBeads™ IDA resins are based on the iminodiacetic acid (IDA) chelating group.
The resin can easily be charged, before use,with a broad spectrum of divalent or
trivalent transition metal ions, including Ni2+, Co2+, Cu2+ or Zn2+, Fe3+ or Ga3+.
They can then be used for the Immobilized Metal Ion Affinity Chromatography (IMAC)
purification of His-tagged proteins or other proteins with an affinity for metal ions.
The selectivity of the metal-charged resin depends on both the choice of ligand (NTA or IDA)
and the metal ion used. The uncharged resins can also be used for divalent metal ion removal.
Main characteristics of WorkBeads 40 Ni-IDA, WorkBeads 40 Co-IDA,
WorkBeads 40 Cu-IDA and WorkBeads 40 Zn-IDA resins.
|
WorkBeads 40 Ni-IDA |
WorkBeads 40 Co-IDA |
WorkBeads 40 Cu-IDA |
WorkBeads 40 Zn-IDA |
Target substance |
His-tagged proteins, proteins containing histidine cysteine and/or tryptophan amino acid side chains |
|||
Matrix |
Highly cross-linked |
Highly cross-linked |
Highly cross-linked |
Highly cross-linked |
Average particle size1 |
45 μm |
45 μm |
45 μm |
45 μm |
Chelating ligand |
Iminodiacetic acid |
Iminodiacetic acid |
Iminodiacetic acid |
Iminodiacetic acid |
Metal ion |
Nickel (II) |
Cobalt (II) |
Cupper (II) |
Zink (II) |
Metal ion capacity for the chelating ligand2 |
NA |
NA |
50 - 60 μmol Cu 2+/ml |
NA |
Dynamic binding capacity3 |
> 60 mg His6- |
NA |
NA |
NA |
Max flow rate (20 cm |
600 cm/h |
600 cm/h |
600 cm/h |
600 cm/h |
Chemical stability |
Compatible with all standard aqueous buffers used for protein purification, 8 M urea, 6 M guanidine-HCl, non-ionic detergents, 20% ethanol. Chelating substances (e.g. EDTA) will strip off the metal ions. Stripped resin: 10 mM HCl (pH 2), 10 mM NaOH (pH 12),10 mM sodium citrate-HCl (pH 3). |
|||
pH stability |
7 - 9 (working range) |
7 - 9 (working range) |
7 - 9 (working range) |
7 - 9 (working range) |
Storage |
2 to 25 °C |
2 to 25 °C |
2 to 25 °C |
2 to 25 °C |
1. The median particle size of the cumulative volume distribution.
2. Metal ion capacity is determined by frontal analysis at 50% breakthrough using cupper solution.
3. The binding capacity is determined using a BabyBio Ni-NTA 1 ml, equal value is expected for IDA resins.
Product List
Product name |
Size/Volume |
Article Number |
WorkBeads 40 IDA |
Bulk-Media - 25 mL |
40 601 001 |
Bulk-Media - 150 mL |
40 601 003 |
|
Bulk-Media - 1 L |
40 601 010 |
|
WorkBeads 40 Ni-IDA |
Bulk-Media - 25 mL |
40 650 001 |
Bulk-Media - 150 mL |
40 650 003 |
|
Bulk-Media - 1 L |
40 650 010 |
|
WorkBeads 40 Cu-IDA |
Bulk-Media - 25 mL |
40 650 301 |
Bulk-Media - 150 mL |
40 650 303 |
|
Bulk-Media - 1 L |
40 650 310 |
|
WorkBeads 40 Co-IDA |
Bulk-Media - 25 mL |
40 650 401 |
Bulk-Media - 150 mL |
40 650 403 |
|
Bulk-Media - 1 L |
40 650 410 |
|
WorkBeads 40 Zn-IDA |
Bulk-Media - 25 mL |
40 650 501 |
Bulk-Media - 150 mL |
40 650 503 |
|
Bulk-Media - 1 L |
40 650 510 |