The word “Amicogen” consists of the meaning of friend, “AMICO”
in Latin and of gene, “GENE”. We developed innovative biocatalysts
and proteins by applying our proprietary i DNA Evolution™ Technology.
We are a “Bioengineering company just like a Sincere Friend”
who contributes to the human health and the preservation of environment.
Amicogen Biotech R&D Center is expanding its R&D field based on
bio-platform technology, and researchers account for 30% of all employees.
We will lead the Industrial Biotechnology to develop new technologies
that can drive the development of humanity and society,
one step further than others.
Amicogen has developed Special Enzymes for industrial and pharmaceutical products based on the i DNA evolution™.
We want to contribute to the sustainable growth and lifelong health
of humanity by developing New Bio-Ingredientfor Health functional foods
with Special Enzymes and Protein Purification Resin.
As Amicogen started as a bio-venture company, we have focused on
the core competence of R&D and are pursuing sustainable growth
in innovative technologies and products. To increase the value
of enterprise and shareholder, we are continually strengthening our core competencies such as specialty enzyme business, healthcare, protein
purification resin business and others.
Amicogen promotes various activities to realize the value of contributing
to the protection of human health and the environment.
Amicogen is positioning itself as a global biotechnology company
through growth and leaps to create new values.
Amicogen has developed bio innovative technologies and operated the businesses that consider humankind and environment from the perspective of sustainability for the past 20 years. We will continue sustainable development based on Amicogen's environmental soundness, social responsibility and sustainable innovative technology.
Amicogen produces new technologies and values based on
creative thinking and constant technological innovation through human
oriented management. We do our best to ensure that talented individuals
with unique skills and abilities can demonstrate their abilities
according to the nature of their duties.
Amicogen produces new technologies and values based on
creative thinking and constant technological innovation through human
oriented management. We do our best to ensure that talented individuals
with unique skills and abilities can demonstrate their abilities
according to the nature of their duties.
We are developing Bio products and New Bio-Ingredients
using i DNA Evolution™ Technology.
WorkBeads™ 40Q
The WorkBeads™ 40 S and WorkBeads 40 Q resins for ion exchange chromatography are designed for research
and industrial scale purification of proteins, peptides and oligonucleotides by utilizing the difference in their surface charge.
WorkBeads 40 S resin is a strong cation exchanger derivatized with sulfonate ligands, and WorkBeads 40 Q resin
is a strong anion exchanger derivatized with quaternary amine ligands.
These resins demonstrate the property of high-resolution separation while giving low backpressure facilitate
both capture and polishing purification applications in standard bioprocess columns.
• High throughput and purity.
• Reliable and reproducible results.
• High chemical stability for easy cleaning-in-place.
Resin description
WorkBeads are agarose-based chromatographic resins manufactured using a proprietary method
that results in porous beads with a tight size distribution and exceptional mechanical stability.
Agarose based matrices have been successfully used for decades in biotechnology purification,
from research to production scale , due to their exceptional compatibility with biomolecules including proteins, peptides,
nucleic acids and carbohydrates. WorkBeads resins are designed for separations requiring optimal capacity and purity.
WorkBeads 40 S is a strong cation exchange resin derivatized with sulfonates as functional groups.
WorkBeads 40 Q is a strong anion exchanger derivatized with quarternary amines as functional groups.
Main characteristics of the WorkBeads 40 S and WorkBeads 40 Q resins
|
WorkBeads 40 S |
WorkBeads 40 Q |
||
Target substances |
Proteins and peptides |
Proteins, peptides and oligonucleotides |
||
Matrix |
Rigid, highly cross-linked agarose |
|||
Average particle size1 (Dv50) |
45 μm |
|||
Ionic group (ligand) |
Sulfonate (-SO3-) |
Quarternary amine (-N+(CH3)3) |
||
Ionic capacity |
0.18 - 0.25 mmol H+/ml resin |
0.18 - 0.25 mmol Cl-/ml resin |
||
Dynamic binding capacity (DBC) |
130 mg BSA/ ml resin2 |
47 mg BSA/ml resin3 |
||
Max flow rate (20 cm bed height and 5 bar) |
600 cm/h |
|||
Chemical stability |
Compatible with all standard aqueous buffers used for protein purification, 1 M NaOH, 30% isopropanol or 70% ethanol. Should not be stored at < pH 3 for prolonged time |
|||
pH stability |
2 - 13 |
|||
Storage |
2 to 25°C in 20% ethanol |
1. The median particle size of the cumulative volume distribution.
2. Dynamic binding capacity determined at 4-minutes residence time in the presence of 20 mM Na-citrate, pH 4.0.
3. Dynamic binding capacity determined at 2.5-minutes residence time in the presence of 50 mM Tris-HCl, 50 mM NaCl, pH 8.0.
Product List
Product name |
Size/Volume |
Article Number |
WorkBeads 40 Q |
Bulk-Media - 25 mL |
40 100 001 |
Bulk-Media - 200 mL |
40 100 002 |
|
Bulk-Media - 1 L |
40 100 010 |
|
WorkBeads 40 S |
Bulk-Media - 25 mL |
40 200 001 |
Bulk-Media - 200 mL |
40 200 002 |
|
Bulk-Media - 1 L | 40 200 010 |