The word “Amicogen” consists of the meaning of friend, “AMICO”
in Latin and of gene, “GENE”. We developed innovative biocatalysts
and proteins by applying our proprietary i DNA Evolution™ Technology.
We are a “Bioengineering company just like a Sincere Friend”
who contributes to the human health and the preservation of environment.
Amicogen Biotech R&D Center is expanding its R&D field based on
bio-platform technology, and researchers account for 30% of all employees.
We will lead the Industrial Biotechnology to develop new technologies
that can drive the development of humanity and society,
one step further than others.
Amicogen has developed Special Enzymes for industrial and pharmaceutical products based on the i DNA evolution™.
We want to contribute to the sustainable growth and lifelong health
of humanity by developing New Bio-Ingredientfor Health functional foods
with Special Enzymes and Protein Purification Resin.
As Amicogen started as a bio-venture company, we have focused on
the core competence of R&D and are pursuing sustainable growth
in innovative technologies and products. To increase the value
of enterprise and shareholder, we are continually strengthening our core competencies such as specialty enzyme business, healthcare, protein
purification resin business and others.
Amicogen promotes various activities to realize the value of contributing
to the protection of human health and the environment.
Amicogen is positioning itself as a global biotechnology company
through growth and leaps to create new values.
Amicogen has developed bio innovative technologies and operated the businesses that consider humankind and environment from the perspective of sustainability for the past 20 years. We will continue sustainable development based on Amicogen's environmental soundness, social responsibility and sustainable innovative technology.
Amicogen produces new technologies and values based on
creative thinking and constant technological innovation through human
oriented management. We do our best to ensure that talented individuals
with unique skills and abilities can demonstrate their abilities
according to the nature of their duties.
Amicogen produces new technologies and values based on
creative thinking and constant technological innovation through human
oriented management. We do our best to ensure that talented individuals
with unique skills and abilities can demonstrate their abilities
according to the nature of their duties.
We are developing Bio products and New Bio-Ingredients
using i DNA Evolution™ Technology.
WorkBeads™ 40/10000 ACT
WorkBeads™ 40/1000 ACT and WorkBeads 40/10 000 ACT are pre-activated resins
that enable easy and reliable coupling of proteins, peptides and low-molecular weight
substances for the preparation of customized chromatography resins or enzyme reactors.
The bromohydrin active group reacts with thiol, amino and hydroxyl groups.
Two different resin porosities are available to facilitate optimized coupling of ligands of
different sizes, or to optimize the prepared affinity resin for target molecules of different sizes.
• Easy and reliable coupling procedure
• Stable covalent linkage
• Suitable for coupling of ligands containing thiol, amino and hydroxyl groups
Resin description
WorkBeads are agarose-based chromatographic resins manufactured using a proprietary method
that results in porous beads with a tight size distribution and exceptional mechanical stability.
Agarose based matrices have been successfully used for decades in biotechnology,
from research to production scale purification, due to their exceptional compatibility with
biomolecules including proteins, peptides, nucleic acids and carbohydrates.
WorkBeads resins are designed for separations that require optimal capacity and purity.
WorkBeads 40/1000 ACT and WorkBeads 40/10 000 ACT pre-activated resins are
a reliable starting material for the preparation of customized chromatography resins.
Main characteristics of WorkBeads 40/1000 ACT and WorkBeads 40/10 000 ACT resins
| WorkBeads 40/1000 ACT | WorkBeads 40/10 000 ACT |
Target substance | Small molecules and peptides | Small molecules, peptides, proteins, e.g., Immunoglobulins |
Target groups | Thiol, amino, and hydroxyl groups | |
Matrix | Rigid, highly cross-linked agarose | |
Average particle size1 (Dv50) | 45 μm | |
Reactive groups | Bromohydrin | |
Exclusion limit | 1 x 106 kDa (globular proteins) | 10 x 106 kDa (globular proteins) |
Max flow rate (20 cm bed height and 5 Bar) | 700 cm/h | 700 cm/h |
Reactive-groups content | 250 μmol/ml | 150 μmol/ml |
Chemical stability | Buffers pH<8.5; | |
Chemical stability | Compatible with all standard aqueous buffers used for protein purification, | |
pH stability3 | 2 – 13 (after coupling) | |
Storage4 | 2 to 25 °C in 20 % ethanol |
1. The median particle size of the cumulative volume distribution.
2. Avoid substances containing thiol and amino groups.
Substances containing hydroxyl groups will only react if deprotonated.
The unreacted resin is generally stable in alcohols at neutral pH.
3. Agarose matrix and linker. Stability of the coupled substance may differ.
4. The choice of storage conditions for the coupled resin depends on the nature of the ligand.
Product List
Product name | Size/Volume | Article Number |
WorkBeads 40/1000 ACT | Bulk-Media - 50 mL | 40 400 001 |
Bulk-Media - 300 mL | 40 400 003 | |
Bulk-Media - 1 L | 40 400 010 | |
WorkBeads 40/10000 ACT | Bulk-Media - 50 mL | 40 450 001 |
Bulk-Media - 300 mL | 40 450 003 | |
Bulk-Media - 1 L | 40 450 010 |