艾美科健(AMICOGEN)是AMICO(=拉丁语中意为"朋友")+GEN(=Gene,
"基因")的合成词, 公司通过其核心技术即基因进化技术,
致力于成为促进人类可持续发展,
保护地球环境的“真正的朋友”。
艾美科健以独家的基因进化技术为基础(i DNA evolution TM)
开发出工业用·制药用特殊酶产品。
利用特殊酶开发出健康功能食品原料即新型生物材料、
蛋白质提炼用树脂,为人类的可持续发展和健康做贡献。
艾美科健从生物科技企业做起,将核心力量关注在R&D上,
以创新的技术和产品追求可持续增长。
为了提高企业价值和股东价值,
在健康保健·蛋白质提炼树脂等领域不断强化核心力量。
过去的20年来,艾美科健始终从可持续的观点出发,开发出致力于人类和环境的生物创新技术,
从事经营。
艾美科健将以环境健全性、社会责任性、可持续创新技术为基础,推动企业可持续发展。
艾美科健以差异化的R&D技术和品质管理能力
开发新的生物产品和健康保健食品原料。
The WorkBeads™ 40 S and WorkBeads 40 Q resins for ion exchange chromatography are designed for research
and industrial scale purification of proteins, peptides and oligonucleotides by utilizing the difference in their surface charge.
WorkBeads 40 S resin is a strong cation exchanger derivatized with sulfonate ligands, and WorkBeads 40 Q resin
is a strong anion exchanger derivatized with quaternary amine ligands.
These resins demonstrate the property of high-resolution separation while giving low backpressure facilitate
both capture and polishing purification applications in standard bioprocess columns.
• High throughput and purity.
• Reliable and reproducible results.
• High chemical stability for easy cleaning-in-place.
Resin description
WorkBeads are agarose-based chromatographic resins manufactured using a proprietary method
that results in porous beads with a tight size distribution and exceptional mechanical stability.
Agarose based matrices have been successfully used for decades in biotechnology purification,
from research to production scale , due to their exceptional compatibility with biomolecules including proteins, peptides,
nucleic acids and carbohydrates. WorkBeads resins are designed for separations requiring optimal capacity and purity.
WorkBeads 40 S is a strong cation exchange resin derivatized with sulfonates as functional groups.
WorkBeads 40 Q is a strong anion exchanger derivatized with quarternary amines as functional groups.
Main characteristics of the WorkBeads 40 S and WorkBeads 40 Q resins
|
WorkBeads 40 S |
WorkBeads 40 Q |
||
Target substances |
Proteins and peptides |
Proteins, peptides and oligonucleotides |
||
Matrix |
Rigid, highly cross-linked agarose |
|||
Average particle size1 (Dv50) |
45 μm |
|||
Ionic group (ligand) |
Sulfonate (-SO3-) |
Quarternary amine (-N+(CH3)3) |
||
Ionic capacity |
0.18 - 0.25 mmol H+/ml resin |
0.18 - 0.25 mmol Cl-/ml resin |
||
Dynamic binding capacity (DBC) |
130 mg BSA/ ml resin2 |
47 mg BSA/ml resin3 |
||
Max flow rate (20 cm bed height and 5 bar) |
600 cm/h |
|||
Chemical stability |
Compatible with all standard aqueous buffers used for protein purification, 1 M NaOH, 30% isopropanol or 70% ethanol. Should not be stored at < pH 3 for prolonged time |
|||
pH stability |
2 - 13 |
|||
Storage |
2 to 25°C in 20% ethanol |
1. The median particle size of the cumulative volume distribution.
2. Dynamic binding capacity determined at 4-minutes residence time in the presence of 20 mM Na-citrate, pH 4.0.
3. Dynamic binding capacity determined at 2.5-minutes residence time in the presence of 50 mM Tris-HCl, 50 mM NaCl, pH 8.0.
Product List
Product name |
Size/Volume |
Article Number |
WorkBeads 40 Q |
Bulk-Media - 25 mL |
40 100 001 |
Bulk-Media - 200 mL |
40 100 002 |
|
Bulk-Media - 1 L |
40 100 010 |
|
WorkBeads 40 S |
Bulk-Media - 25 mL |
40 200 001 |
Bulk-Media - 200 mL |
40 200 002 |
|
Bulk-Media - 1 L | 40 200 010 |