艾美科健(AMICOGEN)是AMICO(=拉丁语中意为"朋友")+GEN(=Gene,
"基因")的合成词, 公司通过其核心技术即基因进化技术,
致力于成为促进人类可持续发展,
保护地球环境的“真正的朋友”。
艾美科健以独家的基因进化技术为基础(i DNA evolution TM)
开发出工业用·制药用特殊酶产品。
利用特殊酶开发出健康功能食品原料即新型生物材料、
蛋白质提炼用树脂,为人类的可持续发展和健康做贡献。
艾美科健从生物科技企业做起,将核心力量关注在R&D上,
以创新的技术和产品追求可持续增长。
为了提高企业价值和股东价值,
在健康保健·蛋白质提炼树脂等领域不断强化核心力量。
过去的20年来,艾美科健始终从可持续的观点出发,开发出致力于人类和环境的生物创新技术,
从事经营。
艾美科健将以环境健全性、社会责任性、可持续创新技术为基础,推动企业可持续发展。
艾美科健以差异化的R&D技术和品质管理能力
开发新的生物产品和健康保健食品原料。
WorkBeads™ Protein A resin is designed for purification of monoclonal-
and polyclonal antibodies using affinity chromatography technique.
For small scale purification and initial screening in process development we recommend
BabyBio A 1 ml and 5 ml columns prepacked with WorkBeads Protein A resin.
WorkBeads Protein A resin can also be used for applications in other formats,
such as test tube batch adsorption, spin columns, gravity columns or multi-well filter plates.
The resin can be used for immunoprecipitation experiments.
• High dynamic binding capacity for monoclonal and polyclonal antibodies with excellent recovery and purity
• Stronger coupling chemistry; high pH stability and low leakage
• Reliable, reproducible and efficient
Product
WorkBeads are agarose based chromatographic resins manufactured by a proprietary method
that results in porous beads with a tight size distribution and very high mechanical stability.
Agarose based matrices have been successfully used for decades in biotechnology research from
laboratory to production scale, due to their exceptional compatibility with biomolecules including
proteins, peptides, nucleic acids and carbohydrates.
WorkBeads resins are designed for separations requiring optimal capacity and purity.
The recombinant protein A attached to the resin is developed by Medicago
and produced in E. coli under conditions free of components of animal origin
and purified to high purity before coupling.
The protein A is engineered to facilitate an oriented coupling to the matrix.
This allows high binding capacities for target proteins.
The specificity of the recombinant protein A for the Fc region of IgG provides excellent purification.
Each batch of protein A is tested according to stringent requirements.
Main characteristics of WorkBeads Protein A resin.
|
WorkBeads Protein A |
Target substance |
Antibodies (IgG), bound via the Fc-region |
Matrix |
Rigid, highly cross-linked agarose |
Average particle size1 (Dv50) |
45 μm |
Ligand |
Recombinant protein A expressed in E. coli using animal-free medium |
Dynamic Binding Capacity2 (DBC) |
> 40 mg human IgG/ml resin |
Recommended flow rate3 |
250 cm/h |
Max flow rate4 |
500 cm/h |
Chemical stability |
Compatible with all standard aqueous buffers used for protein purification, |
pH stability |
3 - 10 (short term) |
Storage |
2 to 8 °C in 20 % ethanol |