艾美科健(AMICOGEN)是AMICO(=拉丁语中意为"朋友")+GEN(=Gene,
"基因")的合成词, 公司通过其核心技术即基因进化技术,
致力于成为促进人类可持续发展,
保护地球环境的“真正的朋友”。
艾美科健以独家的基因进化技术为基础(i DNA evolution TM)
开发出工业用·制药用特殊酶产品。
利用特殊酶开发出健康功能食品原料即新型生物材料、
蛋白质提炼用树脂,为人类的可持续发展和健康做贡献。
艾美科健从生物科技企业做起,将核心力量关注在R&D上,
以创新的技术和产品追求可持续增长。
为了提高企业价值和股东价值,
在健康保健·蛋白质提炼树脂等领域不断强化核心力量。
过去的20年来,艾美科健始终从可持续的观点出发,开发出致力于人类和环境的生物创新技术,
从事经营。
艾美科健将以环境健全性、社会责任性、可持续创新技术为基础,推动企业可持续发展。
艾美科健以差异化的R&D技术和品质管理能力
开发新的生物产品和健康保健食品原料。
The WorkBeads™ 40 S and WorkBeads 40 Q resins for ion exchange chromatography are designed for research
and industrial scale purification of proteins, peptides and oligonucleotides by utilizing the difference in their surface charge.
WorkBeads 40 S resin is a strong cation exchanger derivatized with sulfonate ligands, and WorkBeads 40 Q resin
is a strong anion exchanger derivatized with quaternary amine ligands.
These resins demonstrate the property of high-resolution separation while giving low backpressure facilitate
both capture and polishing purification applications in standard bioprocess columns.
• High throughput and purity.
• Reliable and reproducible results.
• High chemical stability for easy cleaning-in-place.
Resin description
WorkBeads are agarose-based chromatographic resins manufactured using a proprietary method
that results in porous beads with a tight size distribution and exceptional mechanical stability.
Agarose based matrices have been successfully used for decades in biotechnology purification,
from research to production scale , due to their exceptional compatibility with biomolecules including proteins, peptides,
nucleic acids and carbohydrates. WorkBeads resins are designed for separations requiring optimal capacity and purity.
WorkBeads 40 S is a strong cation exchange resin derivatized with sulfonates as functional groups.
WorkBeads 40 Q is a strong anion exchanger derivatized with quarternary amines as functional groups.
Main characteristics of the WorkBeads 40 S and WorkBeads 40 Q resins
| WorkBeads 40 S | WorkBeads 40 Q | ||
Target substances | Proteins and peptides | Proteins, peptides and oligonucleotides | ||
Matrix | Rigid, highly cross-linked agarose | |||
Average particle size1 (Dv50) | 45 μm | |||
Ionic group (ligand) | Sulfonate (-SO3-) | Quarternary amine (-N+(CH3)3) | ||
Ionic capacity | 0.18 - 0.25 mmol H+/ml resin | 0.18 - 0.25 mmol Cl-/ml resin | ||
Dynamic binding capacity (DBC) | 130 mg BSA/ ml resin2 | 47 mg BSA/ml resin3 | ||
Max flow rate (20 cm bed height and 5 bar) | 600 cm/h | |||
Chemical stability | Compatible with all standard aqueous buffers used for protein purification, 1 M NaOH, 30% isopropanol or 70% ethanol. Should not be stored at < pH 3 for prolonged time | |||
pH stability | 2 - 13 | |||
Storage | 2 to 25°C in 20% ethanol |
1. The median particle size of the cumulative volume distribution.
2. Dynamic binding capacity determined at 4-minutes residence time in the presence of 20 mM Na-citrate, pH 4.0.
3. Dynamic binding capacity determined at 2.5-minutes residence time in the presence of 50 mM Tris-HCl, 50 mM NaCl, pH 8.0.
Product List
Product name | Size/Volume | Article Number |
WorkBeads 40 Q | Bulk-Media - 25 mL | 40 100 001 |
Bulk-Media - 200 mL | 40 100 002 | |
Bulk-Media - 1 L | 40 100 010 | |
WorkBeads 40 S | Bulk-Media - 25 mL | 40 200 001 |
Bulk-Media - 200 mL | 40 200 002 | |
Bulk-Media - 1 L | 40 200 010 |