艾美科健(AMICOGEN)是AMICO(=拉丁语中意为"朋友")+GEN(=Gene,
"基因")的合成词, 公司通过其核心技术即基因进化技术,
致力于成为促进人类可持续发展,
保护地球环境的“真正的朋友”。
艾美科健以独家的基因进化技术为基础(i DNA evolution TM)
开发出工业用·制药用特殊酶产品。
利用特殊酶开发出健康功能食品原料即新型生物材料、
蛋白质提炼用树脂,为人类的可持续发展和健康做贡献。
艾美科健从生物科技企业做起,将核心力量关注在R&D上,
以创新的技术和产品追求可持续增长。
为了提高企业价值和股东价值,
在健康保健·蛋白质提炼树脂等领域不断强化核心力量。
过去的20年来,艾美科健始终从可持续的观点出发,开发出致力于人类和环境的生物创新技术,
从事经营。
艾美科健将以环境健全性、社会责任性、可持续创新技术为基础,推动企业可持续发展。
艾美科健以差异化的R&D技术和品质管理能力
开发新的生物产品和健康保健食品原料。
The WorkBeads™ 100S and WorkBeads 100Q resins for ion exchange chromatography
are designed for industrial purification that requires high flow rate and low backpressure.
The products are intended for use in the purification of proteins, peptides and oligonucleotides
by utilizing the difference in surface charge.
WorkBeads 100S is a strong cation exchanger with sulfonate ligands.
WorkBeads 100Q is a strong anion exchanger with quaternary amine ligands.
• High throughput and scalability
• Reliable and reproducible results
• High chemical stability for easy cleaning-inplace
Resin description
WorkBeads are agarose-based chromatographic resins manufactured using a proprietary method
that results in porous beads with a tight size distribution and exceptional mechanical stability.
Agarose based matrices have been successfully used for decades in biotechnology purification, from research to
production scale, due to their exceptional compatibility with biomolecules including proteins, peptides,
nucleic acids and carbohydrates. WorkBeads resins are designed for separations requiring optimal capacity and purity.
WorkBeads 100S is a strong cation exchange resin derivatized with sulfonates as functional groups.
WorkBeads 100Q is a strong anion exchanger derivatized with quaternary amines as functional groups.
Main characteristics of WorkBeads 100S and WorkBeads 100Q resins
WorkBeads 100S |
WorkBeads 100Q |
|
Target substances |
Proteins and peptides |
Proteins, peptides and oligonucleotides |
Matrix |
Rigid, highly cross-linked agarose |
Rigid, highly cross-linked agarose |
Average particle size1 (Dv50) |
90 - 110 μm |
90 - 110 μm |
Ionic group (ligand) |
Sulfonate (-SO3-) |
Quarternary amine (-N+(CH3)3) |
Ionic capacity |
180 - 250 μmol H+/ml resin |
140 - 200 μmol Cl-/ml resin |
Dynamic binding capacity (DBC) |
>100 mg BSA/ml resin2 |
>40 mg BSA/ml resin3 |
Pressure flow characteristic |
2 bar at 900 cm/h, 25 mm diameter column, 20 cm bed height | |
Chemical stability |
Compatible with all standard aqueous buffers used for protein purification, | |
pH stability |
2 - 13 |
2 - 13 |
Storage |
2 to 25°C in 20% ethanol |
2 to 25°C in 20% ethanol |
1. The median particle size of the cumulative volume distribution.
2. Dynamic binding capacity determined at 4-minutes residence time in the presence of 20 mM Na-citrate, pH 4.0.
3. Dynamic binding capacity determined at 4-minutes residence time in the presence of 50 mM Tris-HCl, 50 mM NaCl, pH 8.0.
Product List
Product name |
Size/Volume |
Article Number |
WorkBeads 100 Q |
Bulk-Media - 25 mL |
10 100 001 |
Bulk-Media - 200 mL |
10 100 002 |
|
Bulk-Media - 1 L |
10 100 010 |
|
WorkBeads 100 S |
Bulk-Media - 25 mL |
10 200 001 |
Bulk-Media - 200 mL |
10 200 002 |
|
Bulk-Media - 1 L |
10 200 010 |