AMICOGEN

특수효소

Specialty enzyme

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특수효소 - 제약용

AMK-GX

Immobilized Penicillin G acylase

Description
It produces 6-APA(6-aminopenicillanic acid) from Penicillin G.

 

 

Standard

 Activitya

 200 U/g wet weight

 Size of immobilization support

 150~300㎛(>95%)

 Water content

 <60%

 Enzyme assay

 aOne unit (U) represents the amount of enzyme required for adding 1㎛ol NaOH per min to adjust pH with degradation of Pen G to 6-APA in 50mM K-phosphate, pH 8.0, at 28℃.

 

 

Application
6-APA production from Penicillin G

 

 

Storage temperature
4~10°C

 

 

Characteristics
·Very high specific activity
·High substrate selectivity
·High stability (reusable more than 800 cycles)
·High production rate of 6-APA (more than 98.5%)​

 

 

Reaction condition

 pH

 7.9~8.0

 Temperature

 28°C

 Solvent

 Water

 Enzyme amount

 7~15 U/ml

 Reaction time

 2~3 hours

 

 

 

Scheme for enzyme reaction

673c2f371d2ded79a1a5a62819b7d86e_1526630 

 

 

Optimal reaction conditions
(Temperature, pH)

673c2f371d2ded79a1a5a62819b7d86e_1526630