AMICOGEN

Special Enzyme

Specialty enzyme

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Special Enzyme - Pharmaceutical

AMG118

Immobilized cephalosporin C acylase

Description
It produces 7-ACA(7-aminocephalosporanic acid) from CPC(cephalosporin C) by one-step.

 

 

Standard

Activitya

 80 U/g wet weight

 Size of immobilization support

 150~300㎛ (>95%)

 Water content 

 <60%

 Enzyme assay 

aOne unit (U) represents the amount of enzyme required for adding 1mol NaOH per min to adjust pH with degradation of CPC to 7-ACA in 20mM K-phosphate buer containing 40mM CPC, pH 8.3, at 25℃.

 

 

Application
7-ACA production from CPC

 

 

Storage temperature

4~10°C

 


Characteristics

·High production rate
·High production rate of 7-ACA (more than 99%)
·High quality of 7-ACA
·High production rate of 7-ACA (more than 99%)​

 

Reaction condition

 pH

 8.2 ± 0.2

 Temperature

 13~14°C

 Solvent

 Phosphate buffer or water

 Enzyme amount

 10 U/ml

 Reaction time 

 1~1.5 hours